Phone

(573) 332-7746

Fax

(573) 339-9709

Location

1723 Broadway, Suite 410
Cape Girardeau, MO 63701

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About Us

About Us – Regional Brain & Spine

Neurosurgical, Pain Management, Weight Management and Physical Medicine & Rehabilitation care across Southeast Missouri

At Regional Brain & Spine, we are dedicated to providing advanced, compassionate, and specialty care. With locations in Cape Girardeau, MO (all specialties), Dexter, MO (Pain Management only) and Farmington, MO (Physiatry/Weight Management only), our practice serves the greater Southeast Missouri area with a commitment to clinical excellence and innovation in the treatment of brain, spine, and peripheral nerve disorders.

We understand that conditions and pain affecting your brain and spine can be life-changing. That’s why we offer a full spectrum of care, from conservative, non-surgical treatment options to advanced surgical interventions, always prioritizing precision, personalized attention, transparency, and support throughout your treatment journey. Our Pain Management and Physiatry teams focus on evidence-based, non-surgical therapies, while our surgical specialists provide expert care when surgery is the best option.

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Meet Our Experienced Neurosurgeons

Our team is led by Dr. Paul Tolentino and Dr. Gina Monaco. They both are board-certified and fellowship-trained neurosurgeons. Both physicians are well-respected in the Missouri medical community and are known for their skill in diagnosing and treating a wide spectrum of neurosurgical conditions, including:

  • Brain tumors
  • Spinal disorders such as herniated discs and spinal stenosis
  • Peripheral nerve issues including carpal tunnel syndrome

Their approach combines advanced surgical techniques with a strong commitment to personalized care.

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Our Philosophy: Compassionate, Patient-Centered Care

At Regional Brain & Spine, our philosophy is grounded in:
  • Trust and Communication: We believe in clear, honest communication with patients and families. You’ll always know your options and be supported in making the best decision for your health.
  • Comprehensive Diagnosis and Treatment: We take the time to perform thorough evaluations and create tailored treatment plans, whether surgical or non-surgical.
  • State-of-the-Art Techniques: Our surgeons are trained in the latest innovations in neurosurgery, allowing us to offer less invasive procedures with quicker recovery times.
  • Collaborative Care: We coordinate with your primary care provider, physical therapist, or pain and rehabilitation specialist to ensure seamless, whole-person care.
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A Trusted Neurosurgical Partner in Your Recovery

Our reputation has been built on successful outcomes, compassionate care, and long-standing relationships with referring physicians and specialists throughout Missouri. Patients choose Regional Brain & Spine for:
  • Proven expertise in complex neurosurgical conditions
  • A personalized, respectful experience at every visit
  • Continuity of care from diagnosis through follow-up
  • Multiple convenient locations and hospital affiliations
We are proud to be affiliated with a top regional hospital and to contribute to the ongoing advancement of neurosurgical care in Southeast Missouri.

Regional Brain & Spine

Serving Cape Girardeau and the surrounding Southeast Missouri communities with integrity, innovation, and expert care.

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Contact Us – Regional Brain & Spine

Looking for expert neurosurgical and spine care in Southeast Missouri, Western Kentucky, or Southern Illinois? Regional Brain & Spine makes it easy to connect with our team. Whether you’re a new patient or already established, we’re here to guide you every step of the way.

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Any patient type, new or established, may call or use our general contact form to request an appointment.

Please note that all Regional Brain & Spine providers accept self referrals.

Our Office Locations

Cape Girardeau, MO (For Neurosurgical care only)

Farmington, MO (Physiatry/Weight Management Only)

Dexter, MO (Pain Management Only)

Serving Patients Across the Region

Regional Brain & Spine proudly provides advanced neurosurgery, pain management, physiatry, and obesity medicine services to patients throughout:

  • Southeast Missouri
  • Western Kentucky
  • Southern Illinois
  • Northeast Arkansas
No matter which location is most convenient for you, our team is committed to delivering compassionate, specialized care close to home.
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Get in Touch Today

Have questions about your appointment, insurance, or services? Call our main office in Cape Girardeau at (573) 332-7746. Our friendly staff will be happy to help you schedule your visit or connect you to the right department.

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